Dynamic light elve full#
Dynamic light elve software#

Spheroid microfluidic cell culture principle Microfluidic chip for spheroid cell culture.Flow sensors ( MFS or a BFS for the best performance).The spheroid cell culture pack contains (customizable):

Dynamic light elve software#

Each instrument is compatible with the others, piloted by the same software and comes with a dedicated user guide for beginner friendly step-by-step setup. The spheroid cell culture pack is highly customizable and can include several instruments that can form the following platform. A commercialized dedicated microfluidic chip for spheroids can also be included. Check our webinar dedicated to microfluidic recirculation for cell biology.Ī MUX distribution valve can also be added to inject different media and drugs. Several methods exist to perform recirculation, a MUX recirculation or a MUX Wire with valves can be used. If you never used microfluidics for biology before, you can read our reviews on microfluidics for cell biology including a beginner friendly review.įor long term experiments like spheroid culture in microfluidic chips, recirculation of medium is needed to keep a constant sufficient shear stress applied to the cells without using large quantities of expensive medium. This is especially important to perfectly control the applied shear stress on the cells to better mimic in vivo conditions. This is the most stable and precise microfluidic solution on the market, especially in comparison to syringe and peristaltic pumps. The Elveflow OB1 mk3+ flow controller provides totally pulseless and fast response flow control coupled with flow rate sensors ( MFSor BFSseries) for feedback loops with the OB1. This beginner friendly microfluidic pack for spheroid culture, observation and screening is combined with the flexible Elveflow software for sequence setting and automation that allows improved reproducibility and sample use optimization. You can read more about the advantages of microfluidics for spheroid culture in the “Application” and the “Why use microfluidic” parts of this page. This plug-and-play pack is perfectly suited for researchers that want to transition from batch static culture to microfluidic dynamic cell culture for single spheroid observation for example. The instruments for microfluidic spheroid cell cultureĮlvesys researchers assembled a microfluidic platform to perfuse and induce spheroid growth with perfectly well controlled parameters.

Dynamic light elve full#

Elveflow experts will help you determine your needs depending on your application and will provide continuous and full customer support for you to fulfill your experiment goals.

This pack can be personalized to cultivate different sorts of spheroids. Microfluidic chips are transparent and can be easily combined with microscopy to observe the growth of the spheroids, furthermore, Elveflow software can be easily integrated with other instruments thanks to open SDK libraries. This pack can be customized depending on your specific needs.

Spheroids can be perfused with microfluidic instruments to obtain better reproducibility, continuous physiological shear stress, long automated culture experiments, use of costly fluids and better control on parameters like pH or temperature which makes it the most efficient method to culture spheroids.Įlveflow assembled a beginner-friendly instrument Pilot Pack with high precision microfluidic instruments including an OB1 flow controller with flow sensors for continuous flow rate control that you can combine with your homemade microfluidic chip or a commercially available one. Drugs can be tested using this type of model without using animals and with better mimicking of cell morphology, physiology and organization in compare with 2D cell culture inside Petri dishes. Spheroids are sphere-shaped cell culture in a 3D scaffold that let cells proliferate and migrate inside the scaffold to reproduce cell configuration that occurs inside the human body. A microfluidic beginner instrument pack for spheroid cell culture